New discovery: Dissolvable sutures after surgery detect inflammation and are loaded with drugs

New discovery: Dissolvable sutures after surgery detect inflammation and are loaded with drugs

New discovery: Dissolvable sutures after surgery detect inflammation and are loaded with drugs

Researchers at the Massachusetts Institute of Technology have created dissolvable sutures that can be loaded with molecular sensors or drugs as needed, to speed recovery after surgery and detect any leaks or errors in their positions.

Researchers at the Massachusetts Institute of Technology took tissues from some animals and used a detergent-based process to wash them and get rid of the cells to get the collagen fibers. in wound healing.

The research team was inspired by the idea after finding surgical sutures that could work well for patients with Crohn’s disease, an inflammatory intestinal disease that, in severe cases, can lead to the removal of parts of patients’ intestines. The researchers hoped that the results of the study would lead to the use of innovative surgical sutures in Variety of surgeries.

In the same context, the study’s chief researcher, professor of mechanical engineering at the Massachusetts Institute of Technology and a gastroenterologist at Brigham and Women’s Hospital, Giovanni Traverso, said: It has been achieved to produce a “biodegradable surgical thread after being modified with a hydrogel layer capable of being a reservoir for sensors.” inflammation, or to drugs such as monoclonal antibodies to treat inflammation.

He added that it is remarkable that the innovative threads also have the ability to retain viable cells for a long time, stressing that these threads help in detecting infections at the wound site quickly and through urine analysis.

The researchers succeeded in incorporating the materials used to treat inflammatory bowel disease into the hydrogel, after both monoclonal antibodies and steroids were packaged into polymers used to control the rate of drug release, and then carried in the hydrogel on the surface of the thread. The researchers say other medications could also be included, including antibiotics or chemotherapy drugs.

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